The next round of the high school football playoffs are set. Div. I features four No. 1 seeds, highlighted by St. Edward vs. unbeaten Mentor. Pairings are details below with regional seedings. All games will be played on Friday, Nov. 21 at 7 p.m.

Division I
Region 1
No. 1 Lakewood St. Edward (10-2) vs. No. 2 Mentor (12-0) at Parma Byers Field at Robert Boulton Stadium

Region 2
No. 1 Middletown (10-2) vs. No. 6 Huber Heights Wayne (9-4) at Trotwood-Madison High School Attorney Michael L. Wright SportsPlex

Region 3
No. 1 Lewis Center Olentangy Orange (12-0) vs. No. 2 Pickerington Central (11-1) at Columbus Historic Crew Stadium

Region 4
No. 1 Cincinnati Elder (12-0) vs. No. 3 Cincinnati St. Xavier (9-2) at Mason High School Tri-Health/Beacon Stadium

Division II
Region 5
No. 1 Akron Archbishop Hoban (10-1) vs. No. 2 Cuyahoga Falls Walsh Jesuit (10-1) at Bedford High School Bearcat Stadium

Region 6
No. 1 Medina Highland (12-0) vs. No. 3 Avon (11-1) at Brunswick High School Brunswick Auto Mart Stadium

Region 7
No. 1 Sunbury Big Walnut (11-1) vs. No. 3 Massillon Washington (9-3) at Zanesville High School Sulsberger Stadium

Region 8
No. 1 Cincinnati Anderson (12-0) vs. No. 3 Trotwood-Madison (8-3) at West Chester Lakota West High School Firebird Stadium

Division III
Region 9
No. 2 Cuyahoga Falls CVCA (11-0) vs. No. 4 Cleveland Villa Angela-St. Joseph (10-1) at Twinsburg High School Tiger Stadium

Region 10
No. 5 Rocky River (11-2) vs. No. 6 Toledo Central Catholic (9-4) at Clyde High School Robert J. Bishop Jr. Stadium

Region 11
No. 1 Columbus Bishop Watterson (11-0) vs. No. 3 Steubenville (9-2) at Newark High School White Field

Region 12
No. 1 London (12-0) vs. No. 2 Tipp City Tippecanoe (12-0) at Fairborn High School Skyhawk Stadium

Division IV
Region 13
No. 1 Perry (10-2) vs. No. 2 Cleveland Glenville (9-3) at Ravenna High School Portage Community Bank Stadium/Harry Gilchrist Field

Region 14
No. 1 Shelby (12-0) vs. No. 2 Galion (11-1) at Mansfield Arlin Field

Region 15
No. 1 New Lexington (11-1) vs. No. 2 Gnadenhutten Indian Valley (11-0) at Coshocton High School Stewart Field

Region 16
No. 1 Cincinnati Indian Hill (12-0) vs. No. 2 Germantown Valley View (11-1) at Fairfield High School Alumni Stadium

Division V
Region 17
No. 1 Youngstown Cardinal Mooney (9-2) vs. No. 2 Girard (12-0) at Canfield South Range High School Rominger Athletic Complex

Region 18
No. 1 Liberty Center (12-0) vs. No. 3 Genoa Area (11-1) at Fostoria High School Memorial Stadium

Region 19
No. 1 Wheelersburg (12-0) vs. No. 3 Nelsonville-York (12-0) at Hamilton Township High School Alumni Stadium

Region 20
No. 2 Lewistown Indian Lake (10-2) vs. No. 8 Richwood North Union (9-4) at Marysville High School IMPACT Stadium

Division VI
Region 21
No. 1 Kirtland (12-0) vs. No. 7 Sugarcreek Garaway (10-2) at Louisville High School Leopard Stadium

Region 22
No. 2 Bascom Hopewell-Loudon (11-1) vs. No. 9 Carey (9-4) at Findlay Donnell Stadium

Region 23
No. 3 West Jefferson (11-1) vs. No. 5 North Robinson Colonel Crawford (12-1) at Marengo Highland High School Covrett Stadium Fishburn Family Field

Region 24
No. 5 Coldwater (9-4) vs. No. 6 Anna (10-3) at Piqua High School Alexander Stadium

Division VII
Region 25
No. 1 McDonald (12-0) vs. No. 3 Mogadore (11-1) at Macedonia Nordonia High School Boliantz Stadium

Region 26
No. 3 Leipsic (11-1) vs. No. 4 Columbus Grove (9-3) at Lima Shawnee High School Shawnee Stadium

Region 27
No. 1 Jeromesville Hillsdale (11-1) vs. No. 11 Danville (8-5) at West Lafayette Ridgewood High School Generals Stadium

Region 28
No. 1 Maria Stein Marion Local (12-0) vs. No. 2 St. Henry (11-1) at Wapakoneta High School Mercy Health VFW Post 8445 Field

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All-Time Playoff History Database: https://ohsaaweb.blob.core.windows.net/files/Sports/Football/history/FootballParticipants.pdf

OHSAA football home: https://ohsaa.org/sports/football

MaxPreps Ohio Football Home (stats, scoreboard): https://www.maxpreps.com/state/football/ohio.htm

Ohio Prep Sports Media Association State Football Notebooks: https://www.ohsaa.org/News-Media/Ohio-Prep-Sports-Media-Association/OPSMA-Weekly-Football-Notebooks